Optimum Sizing Algorithm for an Off Grid Plant Considering Renewable Potentials and Load Profile

The energy demand in remote area cannot be satisfied unless renewable energy based plants are locally installed. In order to be efficient, such projects should be sized on the basis of maximizing the renewable energies exploitation and meeting the consumer needs. The aim of this work is to provide an algorithm-based calculation of the optimum sizing of a standalone hybrid plant composed of a wind generator, a photovoltaic panel, a lead acid-battery bank, and a water tank. The strategy consists of evaluating the renewable potentials (solar and wind). Obtained results are entered as inputs to established generators models in order to estimate the renewable generations. The developed optimal sizing algorithm which is based on iterative approach, computes plant components sizes for which load profile meet estimated renewable generations. The approach validation is conducted for A PV/Wind/Battery based farm located in Sfax, Tunisia. Obtained results proved that the energetic need is covered and only about 4% of the generated energy is not used. Also a cost investigation confirmed that the plant becomes profitable ten years after installation.Article History: Received June 24th 2017; Received in revised form September 26th 2017; Accepted Sept 30th 2017; Available onlineCitation: Brahmi, N., Charfi, S., and Chaabene, M. (2017) Optimum Sizing Algorithm for an off grid plant considering renewable potentials and load profile. Int. Journal of Renewable Energy Development, 6(3), 213-224.https://doi.org/10.14710/ijred.6.3.213-22

In vitro ruminal fermentation, nutritional evaluation and antioxidant activity of some forest shrubs of North West Tunisia for goats

Chemical composition and characteristics of in vitro fermentation were determined for two shrubs (Genista aspalathoides and Rhamnus alaternus) collected from north western Tunisia. The primary and secondary chemical composition was determined and in vitro fermentation parameters were measured in 100 ml glass syringes for 48 hours to determine gas production. There are significant differences in chemical and wall composition for the two shrubs studied (p < 0.05). Rhamnus alaternus is richer in secondary metabolites (59.2 mg GAE / g DM) than Genista aspalathoides and has the highest content of crude protein (CP). Genista aspalathoides had the lowest anti-radical activity since it has the highest levels of secondary metabolites, so it is the most digestible species with the highest value of gas production after 24 hours incubation and released more methane than Rhamnus alaternus. Keywords: Shrub, Chemical composition, in vitro fermentation, antioxidant activity, methan

Etude comparative des huiles essentielles de six variétés des nouvelles obtentions d’agrumes cultivées au Maroc

In this research, the essential oils of six INRA’s citrus varieties, which are mandarines El Marzaka, El Mahdia, El Gharabaouia, El Hamra, El Maamoura and orange Shemsia were compared and analyzed. For this purpose, the oil yield, chemical composition, antioxidant and antimicrobial activity were investigated. The extraction was carried out by hydro-distillation. The highest essential oil yield was obtained for Shemsia (5,63%/ DW). The main components of essential oils were identified by GC-MS and their antioxidant activity was determined by DPPH method. The major component of essential oils is D-Limonene, and the highest antioxidant activity was obtained for Shemsia essential oil (24.02%). Antifungal activity was detected in all varieties and the highest value was identified in El Maamoura, while antibacterial activity was not distinguished. From the obtained results, we note that the essential oils of El Maamoura can be valued as a fungicide in agriculture or in medical field. in addition, El Hamra, can be used in Solar cream industry.Les huiles essentielles de six variétés d’agrumes obtenues de l’INRA du Maroc, et qui sont : les mandarines El Marzaka, El Mahdia, El Gharabaouia, El Hamra, El Maamoura et l’orange Shemsia ont été comparées et analysées. La comparaison a été effectuée en termes de rendement, de composition chimique, d’activité antioxydante et d’activité antimicrobienne de ces huiles essentielles. L’extraction a été effectuée par hydro-distillation. Le rendement en huile essentielle le plus élevé a été obtenu chez la variété Shemsia (5,63%/PS). Les principaux composants des huiles essentielles ont été identifiés par CPG-MS et leur activité antioxydante a été déterminée en testant la capacité de piégeage des radicaux libres par DPPH. Le composant majeur des huiles essentielles est le D-Limonène et la plus haute activité antioxydante a été obtenue pour l'huile essentielle d’El Maamoura (24,02%). L'activité antifongique a été détectée chez toutes les variétés et la valeur la plus élevée a été repérée chez El Maamoura, alors que l'activité antibactérienne n'a été détectée chez aucune variété. À partir des résultats obtenus, nous constatons que l’huile essentielle de la mandarine El Maamoura peut être valorisée sous forme de fongicide dans le domaine d’agriculture ou dans le domaine médical. En plus, la variété El Hamra peut être incorporée dans l’industrie de la fabrication des crèmes solaires

Randomised phase 2 study comparing the efficacy and safety of the oral tyrosine kinase inhibitor nintedanib with single agent ifosfamide in patients with advanced, inoperable, metastatic soft tissue sarcoma after failure of first-line chemotherapy: EORTC-1506-STBSG "ANITA"

Purpose: EORTC-1506-STBSG was a prospective, multicentric, randomised, open-label phase 2 trial to assess the efficacy and safety of second-line nintedanib versus ifosfamide in patients with advanced, inoperable metastatic soft tissue sarcoma (STS). The primary end-point was progression-free survival.Patients/methods: Patients with a variety of STS subtypes were randomised 1:1 to nintedanib (200 mg b.i.d. p.o. until disease progression) or ifosfamide (3 g/m(2) i.v. days 1-3, every 21 days for <= 6 cycles). A Korn design was applied aiming to detect an improvement in median progression-free survival (mPFS) from 3 to 4.5 months (HR = 0.667). An interim look was incorporated to stop the trial for futility if <19 of the first 36 patients treated with nintedanib were progression-free at week 12.Results: At the interim analysis, among the first 36 eligible and evaluable patients randomised for nintedanib, only 13 (36%) were progression-free at week 12. The trial was closed for further accrual as per protocol. In total, 80 patients were randomised (40 per treatment group). The mPFS was 2.5 months (95% CI: 1.5-3.4) for nintedanib and 4.4 months (95% CI: 2.9-6.7) on ifosfamide (adjusted HR = 1.56 [80% CI: 1.14-2.13], p = 0.070). The median overall survival was 13.7 months (95% CI: 9.4-23.4) on nintedanib and 24.1 months (95% CI: 10.9-NE) on ifosfamide (adjusted HR = 1.65 [95%CI:0.89-3.06], p = 0.111). The clinical benefit rate for nintedanib and ifosfamide was 50% versus 62.5% (p = 0.368), respectively. Common treatment-related adverse events (all grades) were diarrhoea (35.9% of patients), fatigue (25.6%) and nausea (20.5%) for nintedanib; and fatigue (52.6%), nausea (44.7%) and vomiting, anorexia and alopecia (28.9% each) for ifosfamide.Conclusion: The trial was stopped for futility. The activity of nintedanib did not warrant further exploration in non-selected, advanced STSs. (C) 2021 The Authors. Published by Elsevier Ltd.Experimentele farmacotherapi

D4.2 Final report on trade-off investigations

Research activities in METIS WP4 include several as pects related to the network-level of future wireless communication networks. Thereby, a large variety of scenarios is considered and solutions are proposed to serve the needs envis ioned for the year 2020 and beyond. This document provides vital findings about several trade-offs that need to be leveraged when designing future network-level solutions. In more detail, it elaborates on the following trade- offs: • Complexity vs. Performance improvement • Centralized vs. Decentralized • Long time-scale vs. Short time-scale • Information Interflow vs. Throughput/Mobility enha ncement • Energy Efficiency vs. Network Coverage and Capacity Outlining the advantages and disadvantages in each trade-off, this document serves as a guideline for the application of different network-level solutions in different situations and therefore greatly assists in the design of future communication network architectures.Aydin, O.; Ren, Z.; Bostov, M.; Lakshmana, TR.; Sui, Y.; Svensson, T.; Sun, W.... (2014). D4.2 Final report on trade-off investigations. http://hdl.handle.net/10251/7676

Gastrointestinal decontamination in the acutely poisoned patient

ObjectiveTo define the role of gastrointestinal (GI) decontamination of the poisoned patient.Data sourcesA computer-based PubMed/MEDLINE search of the literature on GI decontamination in the poisoned patient with cross referencing of sources.Study selection and data extractionClinical, animal and in vitro studies were reviewed for clinical relevance to GI decontamination of the poisoned patient.Data synthesisThe literature suggests that previously, widely used, aggressive approaches including the use of ipecac syrup, gastric lavage, and cathartics are now rarely recommended. Whole bowel irrigation is still often recommended for slow-release drugs, metals, and patients who "pack" or "stuff" foreign bodies filled with drugs of abuse, but with little quality data to support it. Activated charcoal (AC), single or multiple doses, was also a previous mainstay of GI decontamination, but the utility of AC is now recognized to be limited and more time dependent than previously practiced. These recommendations have resulted in several treatment guidelines that are mostly based on retrospective analysis, animal studies or small case series, and rarely based on randomized clinical trials.ConclusionsThe current literature supports limited use of GI decontamination of the poisoned patient

D4.3 Final Report on Network-Level Solutions

Research activities in METIS reported in this document focus on proposing solutions to the network-level challenges of future wireless communication networks. Thereby, a large variety of scenarios is considered and a set of technical concepts is proposed to serve the needs envisioned for the 2020 and beyond. This document provides the final findings on several network-level aspects and groups of solutions that are considered essential for designing future 5G solutions. Specifically, it elaborates on: -Interference management and resource allocation schemes -Mobility management and robustness enhancements -Context aware approaches -D2D and V2X mechanisms -Technology components focused on clustering -Dynamic reconfiguration enablers These novel network-level technology concepts are evaluated against requirements defined by METIS for future 5G systems. Moreover, functional enablers which can support the solutions mentioned aboveare proposed. We find that the network level solutions and technology components developed during the course of METIS complement the lower layer technology components and thereby effectively contribute to meeting 5G requirements and targets.Aydin, O.; Valentin, S.; Ren, Z.; Botsov, M.; Lakshmana, TR.; Sui, Y.; Sun, W.... (2015). D4.3 Final Report on Network-Level Solutions. http://hdl.handle.net/10251/7675